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1

TNF-Î±-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimerâs disease pathology in young Trem2 R47H Â rats

Ren, Siqiang, Breuillaud, Lionel, Yao, Wen, Yin, Tao, Norris, Kelly A, Zehntner, Simone P, D'Adamio, Luciano

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 11.66 MB

2020

2

Role of Amyloid-β and Tau Proteins in Alzheimer’s Disease: Confuting the Amyloid Cascade

Gulisano, Walter, Maugeri, Daniele, Baltrons, Marian A., Fà, Mauro, Amato, Arianna, Palmeri, Agostino, D’Adamio, Luciano, Grassi, Claudio, Devanand, D.P., Honig, Lawrence S., Puzzo, Daniela, Arancio,

Journal:

Journal of Alzheimer's Disease

Year:

2018

Language:

english

File:

PDF, 362 KB

english, 2018

3

Thymic and peripheral apoptosis of antigen-specific T cells might cooperate in establishing self tolerance

Luciano D'Adamio, Katherine M. Awad, Ellis L. Reinherz

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 1.13 MB

english, 1993

4

Increased AβPP Processing in Familial Danish Dementia Patients

Matsuda, Shuji, Tamayev, Robert, D'Adamio, Luciano

Journal:

Journal of Alzheimer's Disease

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

5

Pidotimod Stimulates Natural Killer Cell Activity and Inhibits Thymocyte Cell Death

Migliorati, Graziella, D'adamio, Luciano, Coppi, Germano, Nicoletti, Ildo, Riccardi, Carlo

Journal:

Immunopharmacology and Immunotoxicology

Year:

1992

Language:

english

File:

PDF, 485 KB

english, 1992

6

Proteomic Characterization of a Mouse Model of Familial Danish Dementia

Vitale, Monica, Renzone, Giovanni, Matsuda, Shuji, Scaloni, Andrea, D'Adamio, Luciano, Zambrano, Nicola

Journal:

Journal of Biomedicine and Biotechnology

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

7

Interleukin-2 Induces Apoptosis in Mouse Thymocytes

Graziella Migliorati, Ildo Nicoletti, Maria Cristina Pagliacci, Luciano D'Adamio, Carlo Riccardi

Journal:

Cellular Immunology

Year:

1993

File:

PDF, 401 KB

1993

8

Facilitation of glutamate, but not GABA , release in Familial Alzheimer's APP mutant Knock‐in rats with increased β‐cleavage of APP

Tambini, Marc D., Yao, Wen, D'Adamio, Luciano

Journal:

Year:

2019

File:

PDF, 3.93 MB

2019

9

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

Luca Giliberto, Dawang Zhou, Richard Weldon, Elena Tamagno, Pasquale De Luca, Massimo Tabaton, Luciano D'Adamio

Journal:

Molecular Neurodegeneration

Year:

2008

Language:

english

File:

PDF, 2.37 MB

english, 2008

10

The Familial dementia gene ITM2b/BRI2 facilitates glutamate transmission via both presynaptic and postsynaptic mechanisms

Yao, Wen, Yin, Tao, Tambini, Marc D., D’Adamio, Luciano

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 3.92 MB

english, 2019

11

10.1038/8420

D'Adamio, Luciano, Lacana', Emanuela

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

12

Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP

Raphaëlle Pardossi-Piquard, Agnès Petit, Toshitaka Kawarai, Claire Sunyach, Cristine Alves da Costa, Bruno Vincent, Sabine Ring, Luciano D’Adamio, Jie Shen, Ulrike Müller, Peter St. George Hyslop, Fré

Journal:

Year:

2005

Language:

english

File:

PDF, 780 KB

english, 2005

13

The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism

Li, Mi, Pehar, Mariana, Liu, Yan, Bhattacharyya, Anita, Zhang, Su-Chun, O'Riordan, Kenneth J., Burger, Corinna, D'Adamio, Luciano, Puglielli, Luigi

Journal:

Neurobiology of Aging

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

14

The Intracellular Threonine of Amyloid Precursor Protein That Is Essential for Docking of Pin1 Is Dispensable for Developmental Function

Barbagallo, Alessia P. M., Wang, Zilai, Zheng, Hui, D'Adamio, Luciano, Ginsberg, Stephen

Journal:

Year:

2011

Language:

english

File:

PDF, 595 KB

english, 2011

15

Do BRI2 mutations cause early onset Alzheimer's disease?

Robert Tamayev, Shuji Matsuda, Mauro Fa', Ottavio Arancio, Luciano D'Adamio

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

16

CD3η and CD3ζ are Alternatively Spliced Products of a Common Genetic Locus and are Transcriptionally and/or Post-Transcriptionally Regulated During T-Cell Development

Linda K. Clayton, Luciano D'Adamio, Frank D. Howard, Monica Sieh, Rebecca E. Hussey, Shigeo Koyasu and Ellis L. Reinherz

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.39 MB

english, 1991

17

A role for tau in learning, memory and synaptic plasticity

Biundo, Fabrizio, Del Prete, Dolores, Zhang, Hong, Arancio, Ottavio, D’Adamio, Luciano

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.10 MB

english, 2018

18

APP Is Cleaved by Bace1 in Pre-Synaptic Vesicles and Establishes a Pre-Synaptic Interactome, via Its Intracellular Domain, with Molecular Complexes that Regulate Pre-Synaptic Vesicles Functions

Del Prete, Dolores, Lombino, Franco, Liu, Xinran, D'Adamio, Luciano, Ohno, Masuo

Journal:

Year:

2014

Language:

english

File:

PDF, 789 KB

english, 2014

19

Trem2 Splicing and Expression are Preserved in a Human AÎ²-producing, Rat Knock-in Model of Trem2-R47H Alzheimerâs Risk Variant

Tambini, Marc D., DâAdamio, Luciano

Journal:

Scientific Reports

Year:

2020

File:

PDF, 4.45 MB

2020

20

CD74 interacts with APP and suppresses the production of Aβ

Shuji Matsuda, Yukiko Matsuda, Luciano D'Adamio

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

21

Functional cloning of genes involved in T-cell receptor-induced programmed cell death

Luciano D'Adamio, Emanuela Lacana', Pasquale Vito

Journal:

Seminars in Immunology

Year:

1997

Language:

english

File:

PDF, 110 KB

english, 1997

22

Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

Sara Cipolat, Tomasz Rudka, Dieter Hartmann, Veronica Costa, Lutgarde Serneels, Katleen Craessaerts, Kristine Metzger, Christian Frezza, Wim Annaert, Luciano D'Adamio, Carmen Derks, Tim Dejaegere, Luc

Journal:

Year:

2006

Language:

english

File:

PDF, 1.16 MB

english, 2006

23

Generation and Initial Characterization of FDD Knock In Mice

Giliberto, Luca, Matsuda, Shuji, Vidal, Ruben, D'Adamio, Luciano, Mayeux, Richard

Journal:

Year:

2009

Language:

english

File:

PDF, 3.74 MB

english, 2009

24

PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2

Pellegrini, Luca, Passer, Brent J., Canelles, Matilde, Lefterov, Ilyia, Ganjei, J. Kelly, Fowlkes, B.J., Koonin, Eugene V., D'Adamio, Luciano

Journal:

Journal of Alzheimer's Disease

Year:

2001

File:

PDF, 1.39 MB

2001

25

O1-02-04: Regulation of APP processing by the familial dementia gene BRI2

Luciano D’Adamio, Shuji Matsuda, Yukiko Matsuda, Luca Giliberto

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

26

O3-03-01: Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by AICD

Raphaelle Pardossi-Piquard, Agnes Petit, Julie Dunys, Toshitaka Kawarai, Claire Sunyach, Cristine Alves da Costa, Bruno Vincent, Sabine Ring, Luciano D’Adamio, David Westaway, Jie Shen, Ulrike Müller,

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

27

Amyloid β Protein Precursor (AβPP), but Not AβPP-like Protein 2, Is Bridged to the Kinesin Light Chain by the Scaffold Protein JNK-interacting Protein 1

Matsuda, Shuji, Matsuda, Yukiko, D'Adamio, Luciano

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 457 KB

english, 2003

28

Transgenic Expression of the Amyloid-β Precursor Protein-Intracellular Domain Does Not Induce Alzheimer's Disease–Like Traits In Vivo

Giliberto, Luca, d'Abramo, Cristina, Acker, Christopher Michael, Davies, Peter, D'Adamio, Luciano, Smith, Mark A.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

29

Modeling familial British and Danish dementia

Holly J. Garringer, Jill Murrell, Luciano D’Adamio, Bernardino Ghetti, Ruben Vidal

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

30

APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant

Matsuda, Shuji, Tamayev, Robert, Giliberto, Luca, Arancio, Ottavio, D'Adamio, Luciano

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.22 MB

english, 2011

31

Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimerâs Disease: Sensitivity, Specificity and Potential for Clinical Use

dâAbramo, Cristina, DâAdamio, Luciano, Giliberto, Luca

Journal:

Journal of Personalized Medicine

Year:

2020

File:

PDF, 421 KB

2020

32

Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles

Shuji Matsuda, Yukiko Matsuda, Erik L. Snapp, Luciano D’Adamio

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 2.23 MB

english, 2011

33

Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memory

Biundo, Fabrizio, Ishiwari, Keita, Del Prete, Dolores, D’Adamio, Luciano

Journal:

Neurobiology of Learning and Memory

Year:

2015

Language:

english

File:

PDF, 2.50 MB

english, 2015

34

Interleukin-2 induces apoptosis with a mechanism similar to that of glucocorticoid hormones

Riccardi, Carlo, Nicoletti, Ildo, Pagliacci, Cristina, D'Adamio, Luciano, Migliorati, Graziella

Journal:

Pharmacological Research

Year:

1992

Language:

english

File:

PDF, 89 KB

english, 1992

35

A new model of aging and dementia: Focus on C-terminal domain of amyloid precursor protein and Y682ENPTY687 motif

Matrone, Carmela, D'Adamio, Luciano

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

36

Tyr 682 on APP intracellular domain modulates NGF signaling

Matrone, Carmela, La Rosa, Luca, Barbagallo, Alessia, Mercanti, Delio, Chao, Moses, Calissano, Pietro, D'Adamio, Luciano

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 52 KB

english, 2011

37

β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

Robert Tamayev, Shuji Matsuda, Ottavio Arancio, Luciano D'Adamio

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 631 KB

english, 2012

38

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

Robert Tamayev, Dawang Zhou, Luciano D'Adamio

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

39

Knock-in rats with homozygous PSEN1 L435F Alzheimer mutation are viable and show selective Î³-secretase activity loss causing low AÎ²40/42, high AÎ²43

Tambini, Marc D, D'Adamio, Luciano

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 5.71 MB

2020

40

Downregulation of enkephalin-mediated inflammatory responses by CDl0/neutral endopeptidase 24.11

Shipp, Margaret A., Stefano, George B., D'Adamio, Luciano, Switzer, Stephanie N., Howard, Frank D., Sinisterra, Juan, Scharrer, Berta, Reinherz, Ellis L.

Journal:

Year:

1990

File:

PDF, 386 KB

1990

41

Generation of an Apoptotic Intracellular Peptide by γ-Secretase Cleavage of Alzheimer's Amyloid ß Protein Precursor

Passer, Brent, Pellegrini, Luca, Russo, Claudio, Siegel, Richard M., Lenardo, Michael J., Schettini, Gennaro, Bachmann, Martin, Tabaton, Massimo, D'Adamio, Luciano

Journal:

Journal of Alzheimer's Disease

Year:

2000

Language:

english

File:

PDF, 2.27 MB

english, 2000

42

Tuning of glutamate, but not GABA, release by an intra-synaptic vesicles APP domain whose function can be modulated by β- or α-secretase cleavage

Yao, Wen, Tambini, Marc D, Liu, Xinran, D'Adamio, Luciano

Journal:

Journal of Neuroscience

Year:

2019

Language:

english

File:

PDF, 7.32 MB

english, 2019

43

β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

Robert Tamayev, Shuji Matsuda, Luciano D’Adamio

Journal:

Molecular Neurodegeneration

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

44

Role of Cystatin C in Neuroprotection and Its Therapeutic Implications

Luciano D'Adamio

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

45

APP may act as a substrate and a recognition unit for CRLA CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration

Del Prete, Dolores, Rice, Richard C., Rajadhyaksha, Anjali M., D'Adamio, Luciano

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 8.91 MB

english, 2016

46

The intracellular localization of amyloid β protein precursor (AβPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AβPP and alternative splicing

Ghersi, Enrico, Vito, Pasquale, Lopez, Peter, Abdallah, Mona, D'Adamio, Luciano

Journal:

Journal of Alzheimer's Disease

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

47

T-cell receptor isoforms and signal transduction

Shigeo Koyasu, Luciano D'Adamio, Linda K. Clayton, Ellis L. Reinherz

Journal:

Current Opinion in Immunology

Year:

1991

Language:

english

File:

PDF, 880 KB

english, 1991

48

Facilitation of glutamate, but not GABA , release in Familial Alzheimer's APP mutant Knock‐in rats with increased β‐cleavage of APP

Tambini, Marc D., Yao, Wen, D'Adamio, Luciano

Journal:

Year:

2019

Language:

english

File:

PDF, 3.93 MB

english, 2019

49

Generation of mouse natural killer (NK) cell activity: Effect of interleukin-2 (IL-2) and interferon (IFN) on the in vivo development of natural killer cells from bone marrow (BM) progenitor cells

Carlo Riccardi, Antonio Giampietri, Graziella Migliorati, Lorenza Cannarile, Luciano D'Adamio, Ronald B. Herberman

Journal:

International Journal of Cancer

Year:

1986

Language:

english

File:

PDF, 956 KB

english, 1986

50

Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of β-APP

Philip E Tarr, Cristina Contursi, Roberta Roncarati, Cristiana Noviello, Enrico Ghersi, Meir H Scheinfeld, Nicola Zambrano, Tommaso Russo, Luciano D'Adamio

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 149 KB

english, 2002

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